1. Bruising. Bruising is a common cause of buttock pain. · 2. Muscle strain. Your buttocks are made up of three muscles: the gluteus maximus, gluteus medius, and. an exercise program to provide optimal muscle support around the joints; advice regarding short term bracing or taping–only appropriate for short term use and. Patients with piriformis syndrome complain of buttock pain with or without pain radiating to the leg. Numbness, dysthesia, and weakness in. Learn about the diseases and conditions that may cause pain in the buttocks, and read about the medications used in the treatment of buttock pain. Get medical attention right away if: The pain in your buttock, thigh, or lower leg is combined with numbness; You have trouble controlling your foot You have. If someone has this kind of discomfort, it is advisable to find the cause and the right medical treatment. Though most causes of buttock. Piriformis syndrome causes pain in the buttocks and hip. has this kind of discomfort, it is advisable to find the cause and the right medical treatment. Piriformis Syndrome. The Piriformis is a small, flat muscle located deep in the buttock (underneath the gluts). · Proximal Hamstring. Buttock pain includes any type of discomfort in the area of the buttocks. The buttocks are made up of three gluteal muscles behind the pelvis that help. Right buttock pain developed in a year-old man, radiating to the lateral thigh and pretibial area. The pain worsened when he walked. Within a few weeks.